Palace Hotel may refer to:
- Australia
- Palace Hotel, Childers, Queensland
- Palace Hotel, Perth, Western Australia
- Palace Hotel, Kalgoorlie, Western Australia
- Canada
- Palace Hotel, Nanaimo, former hotel (c.1889) and now pub at 275 Skinner Street
- Palace Hotel, Vancouver, former slumhouse at 37 West Hastings Street
- Palace Arms Hotel, a low-frills hotel in Toronto c. 1892 at 950 King Street West
- China
- Peace Hotel South Building, formerly Palace Hotel, in Shanghai, China
- Denmark
- Palace Hotel (Copenhagen), Denmark
- Finland
- Palace Hotel, Helsinki, Finland
- Hungary
- Palace Hotel, Miskolc, Hungary
- Japan
- Palace Hotel, Tokyo, Japan
- Poland
- Palace, a hotel in Poland used by the Gestapo during the Nazi occupation, where Jadwiga ApostoÅ was brought
- United Kingdom
- Refuge Assurance Building, now Palace Hotel, Manchester, England, UK
- Palace Hotel, London, now part of 1 Palace Street
- United States
- Palace Hotel, San Francisco, California
- Palace Hotel (Ukiah, California), listed on the National Register of Historic Places (NRHP) in Mendocino County, California
- Palace Hotel (Antonito, Colorado), listed on the NRHP in Conejos County, Colorado
- Palace Hotel (Cripple Creek, Colorado), a location in an episode of Haunted History
- Palace Hotel (Butler, Missouri), listed on the NRHP in Missouri
- Palace Hotel (Springfield, Missouri), listed on the NRHP in Greene County, Missouri
- Palace Hotel (Missoula, Montana)
- Palace Hotel (Gallup, New Mexico), listed on the NRHP in McKinley County, New Mexico
- The New York Palace Hotel, New York
- Palace Hotel (Cincinnati, Ohio)
- Lane Hotel (Eugene, Oregon), listed on the NRHP as Palace Hotel
- Palace Hotel (Houston, Texas), listed on the NRHP
See also
- Palace Hotel (film), a 1952 Swiss-German drama film
- Sofitel Winter Palace Hotel, Luxor, Egypt
- Athenee Palace Hilton Bucharest Hotel, Romania
- Kempinski Palace Hotel (Portorož), Slovenia
- Badrutt's Palace Hotel, St. Moritz, Switzerland
- Mardan Palace, Antalya, Turkey
- Birkdale Palace Hotel, Merseyside, England, UK
- Regent Palace Hotel, London, England, UK
- Strand Palace Hotel, London, England, UK
- Brown Palace Hotel (Denver, Colorado)
- Brown Palace Hotel (Mobridge, South Dakota)